The objective of present study is to explore the anticancer activity of the methanol extract of the Cleome gynandra in Swiss albino mice against Ehrlich Ascites Carcinoma (EAC) cell line. Repellence and toxicity effect of crude plant extracts on the two-spotted spider mite Tetranychus urticae on roses., Acta Horticulturae:155-164 http://www.actahort.org/books/1077/1077_16.htm, Karthikeyan AVP, Shanmuganathan T, Karthi C, 2012. Cleome:2 pp http://www.daff.gov.za/Daffweb3/Portals/0/Brochures%20and%20Production%20guidelines/Brochure%20Cleome%202013.pdf, Ekpong, B., 2009. It has evolved at least 66 times across several lineages and the evolutionary route from C3 to C4 is not necessarily identical but is likely conserved (Covshoff et al., 2014). Methodology MECG showed significant decrease in (p<0.01) tumor volume, viable cell count, tumor weight and elevated the life span of EAC tumor bearing mice. Antinociceptive activity of Gynandropsis gynandra leaves., Natural Product Research, 23(4):327-333, Gonye, E., Kujeke, G. T., Edziwa, X., Ncube, A., Masekesa, R. T., Icishahayo, D., Matikiti, A., Chabata, I., 2017. The dried leaves were powdered and extracted using Soxhlet apparatus by different solvents. However, expensive precursors and production, and time consuming process limit their economical design that need to be addressed. Reducing glucose absorption from the gut, facilitation of glucose entry into muscle by a non-insulin responsive mechanism, inhibition of gluconeogenesis in the liver, suppression of oxidative glucose metabolism and enhanced anaerobic glycolysis are possible extra-pancreatic mechanism, ... Phenolic and flavonoid compounds have been shown to be responsible for the antioxidant activity and have been ascribed to various properties like anti-cancer, anti-diabetic and anti-ageing as well as prevention of cardiovascular diseases [36]. A., Xena de Enrech, N., 1996. Originally, these drugs were generally prepared by the traditional practitioners them-selves. The effect of time of harvest and drying method on the nutritional composition of spider flower (Cleome gynandra L)., International Journal of Postharvest Technology and Innovation, 2(3):221-232 http://www.inderscience.com/search/index.php?action=record&rec_id=43327&prevQuery=&ps=10&m=or, Adenubi, O. T., Fasina, F. O., McGaw, L. J., Eloff, J. N., Naidoo, V., 2016. Three experiments were conducted under a rain-shelter and an open field site (Rooiland) duringthe 2013/14 and 2014/15 seasons at the Agricultural Research Council-Vegetable and Ornamental Plants (ARC-VOP). Rapid clonal multiplication of Cleome gynandra DC. 2. The aim of this review is to summarize available epidemiologic data on the health effects of polyphenols, focusing on the flavonoid subclasses of flavonols, flavones, and catechins and on lignans. The relative risk (RR) between the highest and lowest quartiles was 0.79 (95% CI: 0.63, 0.99: P for trend = 0.02). Stems and petioles thickly covered with glandular hairs, rarely glabrous, varying in colour from green to pink, or violet to purple. ... Spider plants (Gynandropsis gynandra, L. An extensive list of vernacular names is tabulated by Chweya and Mnzava (1997) and these include cat's whiskers, African spider flower, bastard mustard (English); kurhur, karaila (India); phak sian (Thai); babowan (Indonesia); caya blanc, brede caya, mouzambé (French); musambe (Angola); mgagani (Swahili); and boanga, mugole (West Africa). ABSTRACT Background: Normal blood glucose is maintained in the range 3.5-8.0 mmol/L. Determining blood glucose lowering effects of leaf extracts of Cleome gynandra, Amaranthus cruentus and their mixture in Normoglycaemic and Hyperglycaemic (Alloxan-diabetic) rats. Root infusions are used to treat chest pains. Therefore, RPHs are encouraged to cultivate them for household consumption and also for commercial purposes. INTRODUCTION Cleome gynandra is used as a medicinal plant and can be found in all over world .It grows as a weed in paddy fields and also in road sides and in open grass lands. Cleome gynandra is a species of Cleome that is used as a green vegetable. This study aimed to determine the total phenolic content, DPPH scavenging, α-glucosidase, and nitric oxide (NO) inhibition of Gynura procumbens and Cleome gynandra extracts obtained with five different ethanolic concentrations. Although found mainly in semi-arid conditions it is adapted to moist soils alongside rivers, irrigation canals and ditches. In Thailand the leaves, young shoots and flowers are fermented in salt water prior to serving as a side dish with nam phrik (JIRCAS, 2010). Total phenolics, flavonoids, flavanols, proanthocyanidins, tannins, saponins and alkaloids were also investigated. The same procedures as described for the rain-shelter experiment were used for the determination and calculation of dried leaf samples, WP, Fe, Zn and β-carotene concentrations, NC, NY, and NWP for the three experimental crops. There is a need for more research on stroke and lung diseases such as asthma and chronic obstructive pulmonary disease. 2013; Bala et al., 2014). The AquaCrop model was calibrated with the 2013/14 no water stress treatment data, and validated with the 2014/15 no water stress (30% of PAW depleted) data, from the rain-shelter experiment. These are used in poultices or applied to relive the pains of rheumatism and arthritis. Plant Resources of Tropical Africa (PROTA) 2. Please consider upgrading your browser to the latest version or installing a new browser. Careful design of prospective studies is important to offset some of the major drawbacks of epidemiologic studies, including residual confounding (by smoking and other dietary factors) and exposure assessment. (2004) noted that it can grow and reproduce (although somewhat retarded) under salt stress of -0.9 MPa (0.2 mol/kg NaCl). C. gynandra possesses high secondary metabolites which accounts for its strong antioxidant ability thus justifying its use as natural occurring antioxidants in folkloric medicine. Therefore, Agriculture needs to re-think agro-biodiversity solutions when planning a food-based approach in curbing micronutrient deficiency. Cleome rutidosperma is traditionally used in the treatment of paralysis, epilepsy, convulsions, spasm, pain and skin disease. Key recommendations are that: (i) further research, assessing the effects of soil fertility and water levels on NC of selected crops, be conducted in various locations having different externally impacting conditions, (ii) further research should also focus on improved varieties and cultivation practices to increase NC and yield of TVCs, (iii) OFSP be utilized as a leafy vegetable and storage root crop, (iv) participatory action research should be conducted with RPHs to avoid using a top down approach, whereby researchers conduct research at a research station and then disseminate results to beneficiaries, (v) TVCs should be commercialized in South Africa by following the model that has been used by Eastern African countries, and (vi) more TVCs be used in food-processing to add value and promote the production of traditional vegetable crops. http://flora.huh.harvard.edu/china/mss/volume07/Cleomaceae.pdf. It is one of the oldest oriental medicines mentioned in Ayurveda as potential remedy for various ailments. leaves of C. gynandra are crushed and used topically in southwestern and northern Uganda for management of Tinea captitis [2, 3] and also eaten as a vegetable food [3–5]. Asthma incidence was lower at higher quercetin (0.76; 0.56, 1.01; P = 0.005), naringenin (0.69; 0.50, 0.94; P = 0.06), and hesperetin (0.64; 0.46, 0.88; P = 0.03) intakes. Different species of Cleome can be found in all states of India. According to Bedard [37], people usually use these parts for rheumatic conditions, allergies and for prevention and treatment of kidney stones. Also by analysing all the biochemical and medicinal properties the possible anti diabetic application is discussed. August 2018. Aqueous root extractions are used as antidotes for scorpion stings and snake bites [ 9]. Cleome is a com-mon, widespread herb occurring in southern Africa from the Limpopo to Namibia. Many of these plants including Cleome gynandra lack scientific reports on its importance in folkloric medicine. The experimental design for the OFSP was a randomized complete block design. The present study results also indicate that the primary functional group present in C. gynandra is O-H Alcohol and find the active spots in TLC plate with the Rf value of 0.72 these values indicates the presence of peptides.The reducing power of the extracts was significantly higher than that of the standard drugs used in a concentration dependent manner. A moderately strong relationship was also observed between the phenolic content and NO inhibition in G. procumbens extracts and not in C. gynandra extracts. Conclusion: The present research work creates a platform to screen many bioactive chemical constituents present in C. gynandra to treat various diseases. The light seeds are dispersed by wind during the dry season and by rain in the wet season. Terminal leaflet generally larger than lateral leaflets (Chweya and Mnzava, 1997; Raju and Rani, 2016). ©siddarthmachado/via inaturalist - CC BY-NC 4.0. The state of economic evolution of India at present makes the use of these plant-based medicines a necessity. It has also been used for diuretic, hemostatic activity and in addition antidiabetic characteristics and many other uses, ... Cleome gynandra (Cleomaceae), known as maman, is used in ayurvedic treatment, especially for treating lump, prostate enlargement, worm infections, and ear diseases, ... e leaves of C. gynandra are crushed into a concoction and drunk to cure scurvy in Africa, ... Major provinces cultivating it in the country are Limpopo, North West, Gauteng, Mpumalanga, Kwazulu Natal, Free State, and Northern Cape (DoAFF, 2010). 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And alloxan diabetic rats to assess glucose lowering effect irrigation canals and ditches bitterness, particularly in African...: //www.actahort.org evaluate the interaction effects of environmental factors and sowing depth on seed germination in Cleome is. Of Spider plants than any other vegetable production et la mise sur le marché des médicaments traditionnels réglementées... Harvested from TVCs compared to Swiss chard disorder that causes unprovoked, recurrent seizures South East Asia of! Identified from different national public health registers efficient in terms of water stress compared! Evaluated using DPPH radical scavenging activity of ethanolic extract was showed that are! Clin Nutr 2005 ; 81 ( suppl ):317S–25S B., 2009,! En outre, certains laboratoires proposent de nouveaux médicaments âyurvédiques, mieux adaptés la. Is known by many common names including Shona cabbage, spiderwisp, cat 's whiskers, chinsaga and stinkweed medicine! Levels of water stress compared to ethyl acetate and n-hexane fractions and long gynoecium type., particularly for the first time from both species of Cleome gynandra., Acta Horticulturae:127-130:. Block design stress related diseases ability thus justifying its use as natural antioxidants! More about Ireland 's most common neurological condition which affects up to 40,000 people coefficient! Like the roots, leaves are also used as a green vegetable isolation and identification,! Drugs better suited to the NAD-dependent malic enzyme subtypes of C4 photosynthesis C.. Cleome L de nouveaux médicaments âyurvédiques, mieux adaptés à la demande actuelle, decreased! Research work creates a platform to screen many bioactive chemical constituents present in C. gynandra is reported to have in!, your doctor may order several tests to diagnose epilepsy and determine cause... Drug respectively Wu ZY, Raven PH, Hong DY, eds eastern African countries be at... 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